Part of normal body flora, colony morphology: opaque, round, buttery, golden
yellow, convex, beta hemolytic, ferments manitol salt agar, small variant colonys
may appear after antibiotic treatment, coagulase pos, DNase, thermonuclease pos.
diseases: impetigo, toxic shock syndrome, food poisoning, pneumonia,
meningitis, colonizes medical equipment (IV, catheters), Methicillin resistant
staph arueus: nosocomial infections.
creamy white, beta hemolytic colonies typical of Staphylococcus aureus
Opaque:مات
Buttery: روغنی
Convex: محدب
Staphylococcus aureus virulence factors
a) Alpha hemolysin: lyses RBC, skin cell death, nerve damage
b) Beta hemolysin: lyses RBC
c) Gamma hemolysin: lyses RBC, neurtrophils, macrophages
d) Delta hemolysin: lyses RBC, cell membranes
e) Toxic shock syndrome toxin 1: fever, t lymph proliferation, lethal effect of endotoxin
f) Staph enterotoxins: vomiting, t-lymph proliferation, fever
g) Leukocidin: lyses neutrophils and macrophages
h) Exfoliative toxins: shedding of epidermis, t-lymph proliferation
gram stained of Staphylococcus aureus

